Against Me! is an American punk rock band formed in Gainesville, Florida, United States, in 1997 by singer and guitarist Laura Jane Grace. Since 2001, the band's lineup has also included guitarist James Bowman. After releasing three studio albums through independent record labels, Against Me! moved to Sire Records for 2007's New Wave, which reached no. 57 on the Billboard 200. In 2011, the band launched their own record label, Total Treble Music, through which to release future albums.

In 2012, Grace publicly came out as transgender, beginning a transition to living as a woman and dropping her birth name. After a long period of line-up changes and uncertainty surrounding the band's future, their sixth studio album, Transgender Dysphoria Blues, was released independently in January 2014 to critical and commercial acclaim. The band's seventh full-length, Shape Shift with Me, was released September 16 2016.